Does Enalapril Prevent Peritoneal Fibrosis Induced by Hypertonic (3.86%) Peritoneal Dialysis Solution?

21 albino Wistar rats

10 cc 3.86% dextrose peritoneal dialysis solution intraperitoneally plus 100 mg/L enalapril in drinking water for 4 weeks

Control group (10 mL isotonic saline intraperitoneally) and Dextrose group (10 mL 3.86% dextrose peritoneal dialysis solution intraperitoneally)

Peritoneal function (dialysate-to-plasma urea ratio, glucose reabsorption, ultrafiltration volume, dialysate protein, TGFbeta1, and CA125) and morphology (peritoneal thickness) at 4 weekssurrogate