September 1, 1974The Journal of PhysiologyOpen Access

Circulatory effects of deep inspirations, blocked expirations and positive pressure inflations at equal transpulmonary pressures in conscious dogs

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Population

8 dogs (6 conscious dogs, plus 2 additional dogs in acute conditions)

Design

Preclinical

Authors

ACAndré A. CharlierUniversidade de Ribeirão Preto PJP. JauminUCLouvain HPH. PouleurMcMaster University

Discussion

Member takes

Implication

Respiratory mechanics may reduce LV output independent of LA pressure in conscious dogs; leaves open translation to human cardiopulmonary physiology.

Structured PICO

Population

8 dogs (6 conscious dogs, plus 2 additional dogs in acute conditions)

Intervention

Respiratory maneuvers including deep inspirations, blocked expirations, and constant endotracheal positive pressure inflations at equal transpulmonary pressures (around 10.2 cm H2O)

Outcome

Beat-by-beat left and right ventricular ejections, pulmonary arterial, left atrial and aortic mean transmural pressures, and concomitant intrathoracic and tracheal pressuressurrogate

Mechanical factors, specifically changes in intrathoracic pressure during respiratory maneuvers, play a leading role in altering ventricular output and outflow impedance in conscious dogs.

Cite This Study

Charlier et al. (1974) studied this question.

synapsesocial.com/papers/6a6feb0e8031ec7bb1dc0278 https://doi.org/10.1113/jphysiol.1974.sp010673

View Full Paper

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Implication

Respiratory mechanics may reduce LV output independent of LA pressure in conscious dogs; leaves open translation to human cardiopulmonary physiology.

Circulatory effects of deep inspirations, blocked expirations and positive pressure inflations at equal transpulmonary pressures in conscious dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Circulatory effects of deep inspirations, blocked expirations and positive pressure inflations at equal transpulmonary pressures in conscious dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider