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Loperamide, diphenoxylate, and codeine phosphate in chronic diarrhoea Loperamide, diphenoxylate, and codeine phosphate are commonly used to treat chronic diarrhoea.There have been only two controlled studies that compare loperamide with diphenoxylate in patients with chronic diarrhoea,' 2 and there has been no comparison of loperamide with codeine phosphate for this condition.
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Shee et al. (1980) studied this question.
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