Answers are grounded in this paper and cite their sources.
“Smart” self-assembly of several chiral diols and an achiral pre-catalyst results in the formation of a highly enantioselective catalyst for the carbonyl–ene reaction (a). The assembly is not influenced by the order of addition of the components and always results in the exclusive formation of a single catalyst, as shown by NMR spectroscopy studies.
No takes yet. Share an insight, caveat, or question.
Mikami et al. (1997) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: