February 1, 1997AJP Heart and Circulatory Physiology

Contribution of red blood cell aggregation to venous vascular resistance in skeletal muscle

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Population

Cat lateral gastrocnemius muscle model

Comparison

Perfusion with blood of normal hematocrit… vs Different perfusion solutions and flow rates

Design

Preclinical

Authors

MCM. CabelUniversity of California, Davis HMH.J. MeiselmanUniversity of Southern California APAleksander S. PopelJohns Hopkins University

Discussion

Member takes

Implication

Does not change clinical practice; leaves open RBC aggregation's role in human venous resistance.

Structured PICO

Population

Cat lateral gastrocnemius muscle model

Intervention

Perfusion with blood of normal hematocrit, acellular solution (12% Dextran 40 in Ringer solution), nonaggregating suspension of red blood cells, or blood with added Dextran 250

Comparator

Different perfusion solutions and flow rates

Outcome

Venous vascular resistance and conductancesurrogate

Red blood cell aggregation contributes significantly to venous vascular resistance in resting skeletal muscle.

Cite This Study

Cabel et al. (1997) studied this question.

synapsesocial.com/papers/6a6fecbd439bab0cabc2f463 https://doi.org/10.1152/ajpheart.1997.272.2.h1020

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Contribution of red blood cell aggregation to venous vascular resistance in skeletal muscle

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Contribution of red blood cell aggregation to venous vascular resistance in skeletal muscle

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider