Population
Anesthetized cats (tibialis anterior limb muscle afferents)
Comparison
Ischemia and acute hypoxemia (PaO2 = 24 mm Hg) vs Normoxic conditions
Design
Preclinical
Authors
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May alter interpretation of muscle afferents in human hypoxemia; leaves open acidosis mechanisms for clinical translation.
Ischemia and acute hypoxemia exert opposite influences on mechanoreceptors and metaboreceptors in cat skeletal muscle, likely mediated by local acidosis.
Lagier‐Tessonnier et al. (1993) studied this question.
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