November 1, 1988Psychological Medicine
Cerebral blood flow and metabolism of oxygen and glucose in young autistic adults
Why the study?
Are there differences in regional cerebral blood flow, oxygen consumption, and glucose consumption between young autistic men and normal controls?
Population
6 young autistic men and normal controls
Comparison
Positron emission tomography (PET) measurement vs Normal controls
Design
Case-control
Authors
Discussion
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Implication
No differences in cerebral metabolism or blood flow detected in young autistic men; leaves open metabolic hypotheses and requires replication before clinical consideration.
Structured PICO
Are there differences in regional cerebral blood flow, oxygen consumption, and glucose consumption between young autistic men and normal controls?
P
Population
6 young autistic men and normal controls
I
Intervention
Positron emission tomography (PET) measurement
C
Comparator
Normal controls
O
Outcome
Regional cerebral blood flow, oxygen consumption and glucose consumptionsurrogate
The study found no evidence of glucose hypermetabolism or altered cerebral blood flow in young autistic men compared to controls.
Cite This Study
Herold et al. (1988) studied this question.