December 1, 1996Clinical Cardiology
QT interval change with age in an overtly healthy older population
Population
96 healthy subjects with normal resting ECGs, no symptoms or signs of heart disease, not on medication…
Design
Cross-sectional
Authors
Discussion
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Implication
QTc prolongation with age may elevate arrhythmia risk in elderly; hypothesis-generating for QT dispersion's prognostic role.
Structured PICO
P
Population
96 healthy subjects (73 women, age range 40-102 years) with normal resting ECGs, no symptoms or signs of heart disease, not on medication affecting cardiac function, normal heart size on chest x-ray, and normal electrolytes.
O
Outcome
Relationship between aging, QT interval, and QT dispersionsurrogate
In healthy individuals, the rate-adjusted QT interval prolongs with increasing age, potentially contributing to higher arrhythmia risk in the elderly, while QT dispersion does not change.
Cite This Study
Reardon et al. (1996) studied this question.