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November 1, 1998Journal of Biological ChemistryOpen Access

Smad4/DPC4 and Smad3 Mediate Transforming Growth Factor-β (TGF-β) Signaling through Direct Binding to a Novel TGF-β-responsive Element in the Human Plasminogen Activator Inhibitor-1 Promoter

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Authors

CSChao-Zhong SongCalifornia Institute for Regenerative MedicineTSTara E. SiokNihon UniversityTGThomas GelehrterUniversity of Michigan

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Song et al. (1998) studied this question.

synapsesocial.com/papers/6a6ff3f95671bbf00bc29ff7https://doi.org/10.1074/jbc.273.45.29287
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta.1991 · 319 citations
  2. 2Induction of plasminogen activator inhibitor-1 in HepG2 human hepatoma cells by mediators of the acute phase response.1994 · 80 citations
  3. 3Plasminogen Activator Inhibitors - A Review2017 · 292 citations