Population
Genetically engineered mouse models of Ryanodine receptors (RyR)
Design
Review
Authors
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RyR mouse models implicate channel roles in arrhythmias and HF; hypothesis-generating and should not yet alter clinical management.
Genetically engineered mouse models have significantly enhanced the understanding of Ryanodine receptor channels in cellular physiology and pathophysiology, including cardiac arrhythmias and heart failure.
Kushnir et al. (2010) studied this question.
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