Why the study?
Is the reversed halo sign on chest CT a reliable indicator of septic pulmonary embolism in patients with IV substance use disorder?
Is the reversed halo sign on chest CT a reliable indicator of septic pulmonary embolism in patients with IV substance use disorder?
The reversed halo sign on chest CT is a frequent and reliable finding that can help differentiate septic PE from other causes of pulmonary infarct in patients with IV substance use disorder.
Reversed halo sign on CT may suggest septic PE in IV substance users; hypothesis-generating for differentiation from other infarcts, pending prospective validation.
Septic PE should be considered in the differential diagnosis of patients with IV substance use disorder presenting with reversed halo sign. The reversed halo sign was reliably and frequently observed on the chest CT scans of patients with IV substance use disorder-related septic PE. Characteristics of reversed halo sign presentation were identified as potential features to differentiate septic PE from other causes of pulmonary infarct manifesting with reversed halo sign.
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Almeida et al. (2019) studied this question.
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