Why the study?
Does sodium cromoglycate reduce the excitation of 'C' fibre sensory nerve endings by capsaicin in the canine lung?
Population
Canine lung model (dogs)
Design
Preclinical
Follow-up
45 min
Authors
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SCG attenuates capsaicin-evoked C-fibre excitation in canine lung; hypothesis-generating for human airway responses and requires clinical confirmation.
Does sodium cromoglycate reduce the excitation of 'C' fibre sensory nerve endings by capsaicin in the canine lung?
Sodium cromoglycate reduces capsaicin-induced excitation of 'C' fibre sensory nerve endings in the canine lung, providing a potential mechanism for its suppression of bronchoconstrictor responses in humans.
Dixon et al. (1980) studied this question.
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