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October 1, 2001DiabetesOpen Access

Phosphorylation-Dependent Nucleocytoplasmic Shuttling of Pancreatic Duodenal Homeobox-1

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Authors

LELucy J. ElrickGlasgow Royal InfirmaryKDKevin DochertyUniversity of Copenhagen

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Elrick et al. (2001) studied this question.

synapsesocial.com/papers/6a6ffc24febe604dd708cc89https://doi.org/10.2337/diabetes.50.10.2244
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Glucose Stimulates Translocation of the Homeodomain Transcription Factor PDX1 from the Cytoplasm to the Nucleus in Pancreatic β-Cells1999 · 220 citations
  2. 2Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.2000 · 68 citations
  3. 3PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin1996 · 200 citations
  4. 4Glucose-dependent Translocation of Insulin Promoter Factor-1 (IPF-1) between the Nuclear Periphery and the Nucleoplasm of Single MIN6 β-Cells1998 · 102 citations