Increase in PDX-1 Levels Suppresses Insulin Gene Expression in RIN 1046–38 Cells*

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.1997 · 35 citations
2. 2The Human Glucokinase Gene β-Cell-Type Promoter: An Essential Role of Insulin Promoter Factor 1/PDX-1 in Its Activation in HIT-T15 Cells1996 · 221 citations
3. 3Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.1993 · 337 citations
4. 4Purification of the β-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells1996 · 175 citations