Why the study?
Does ginkgolide B reduce atherogenesis and vascular inflammation in ApoE-/- mice?
Does ginkgolide B reduce atherogenesis and vascular inflammation in ApoE-/- mice?
Ginkgolide B reduces atherogenesis and vascular inflammation in a preclinical model, likely via inhibition of the PI3K/Akt pathway in activated platelets, with efficacy comparable to aspirin.
Supports testing ginkgolide B in human atherosclerosis trials; leaves open clinical translation from this preclinical model.
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Liu et al. (2012) studied this question.
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