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January 23, 2014PLoS PathogensOpen Access

Preservation of Tetherin and CD4 Counter-Activities in Circulating Vpu Alleles despite Extensive Sequence Variation within HIV-1 Infected Individuals

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Authors

SPSuzanne PickeringKing's College LondonSHStéphane HuéUniversity of LondonEKEun‐Young KimNorthwestern University

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Pickering et al. (2014) studied this question.

synapsesocial.com/papers/6a6ffc80ac440176ef28a382https://doi.org/10.1371/journal.ppat.1003895
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein1989 · 278 citations
  2. 2A Cytoplasmic Tail Determinant in HIV-1 Vpu Mediates Targeting of Tetherin for Endosomal Degradation and Counteracts Interferon-Induced Restriction2012 · 106 citations
  3. 3Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and Counteraction2011 · 103 citations
  4. 4Anti-tetherin activities in Vpu-expressing primate lentiviruses2010 · 72 citations
  5. 5Modulation of HIV-1-host interaction: role of the Vpu accessory protein2010 · 134 citations