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March 29, 2012PLoS PathogensOpen Access

A Cytoplasmic Tail Determinant in HIV-1 Vpu Mediates Targeting of Tetherin for Endosomal Degradation and Counteracts Interferon-Induced Restriction

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TKTonya KueckMax Planck Institute for the History of ScienceSNStuart J. D. NeilGuy's Hospital

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Kueck et al. (2012) studied this question.

synapsesocial.com/papers/6a6ffc80ac440176ef28a387https://doi.org/10.1371/journal.ppat.1002609
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Also Consider

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  1. 1Simultaneous Binding of PtdIns(4,5)P 2 and Clathrin by AP180 in the Nucleation of Clathrin Lattices on Membranes2001 · 738 citations
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  4. 4HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation2009 · 314 citations
  5. 5Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking2009 · 330 citations