Why the study?
Does endothelial dysfunction predict major adverse cardiac and cerebrovascular events in nondiabetic peritoneal dialysis patients?
Population
143 nondiabetic peritoneal dialysis (PD) patients and 32 controls
Comparison
Endothelial dysfunction measured by brachial… vs Higher FMD (>2.9%)
Design
Cohort
Follow-up
mean 42 months
Authors
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May aid MACCE risk stratification via FMD in nondiabetic PD patients; leaves open prospective validation and therapeutic implications.
Does endothelial dysfunction predict major adverse cardiac and cerebrovascular events in nondiabetic peritoneal dialysis patients?
Impaired brachial flow-mediated dilation is an independent predictor of major adverse cardiovascular events in nondiabetic peritoneal dialysis patients, suggesting its utility for cardiovascular risk stratification.
Lee et al. (2014) studied this question.
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