Why the study?
Is a decreased level of serum soluble Klotho associated with arterial stiffness in patients with chronic kidney disease?
Is a decreased level of serum soluble Klotho associated with arterial stiffness in patients with chronic kidney disease?
Decreased serum soluble Klotho levels are independently associated with arterial stiffness in patients with chronic kidney disease, suggesting its potential as a biomarker for vascular dysfunction.
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Lower Klotho associated with arterial stiffness in CKD; hypothesis-generating and requires prospective validation before clinical use.
Kitagawa et al. (2013) studied this question.
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