What question did this study set out to answer?

To investigate the role of the MAR1 locus in mating type regulation and sterility in Saccharomyces cerevisiae.

September 1, 1979GeneticsOpen Access

MAR1—A REGULATOR OF THE HM a AND HMα LOCI IN SACCHAROMYCES CEREVISIAE

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Experimental evidence reveals MAR1's role in regulating mating types in Saccharomyces cerevisiae, suggesting genetic implications.

To investigate the role of the MAR1 locus in mating type regulation and sterility in Saccharomyces cerevisiae.
Mutation mapping identified MAR1 position on linkage group IV between trp1 and cdc2.
Analysis of haploid strains with mar1-1 genotype and their mating type expression.
Assessment of mating behavior through 'rare mating' with standard strains.
Sterile strains MATalpha HMalpha HMa mar1-1 and MATa HMalpha HMamar1-1 display spermlessness.
Nonmating phenotype observed in mar1-1 mutants, similar to MATa/MATalpha diploids.
Findings support that HMalpha and hma carry MATa information; HMa and hmalpha carry MATalpha information.

Klar et al. (1979) studied this question.

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