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This study was designed to explore the biological characteristics of a new oral streptococcus species Streptococcus oligofermentans. Plaque samples were collected from caries-free and caries-active subjects. S. oligofermentans was selectively grown on Mitis salivarius agar plates and identified by using 2-step PCR and was isolated from 38% of 18 subjects. Isolates were found mostly on healthy tooth surfaces. S. oligofermentans had weaker abilities in acid production and demineralizing hydroxyapatite. When Streptococcus mutans was coincubated with S. oligofermentans, total number, acid production and calcium release were significantly inhibited. In conclusion, inhibition of S. mutans could be a beneficial biological characteristic of S. oligofermentans in oral microecology.
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Zhang et al. (2010) studied this question.
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