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January 1, 2001Arthritis & Rheumatism

Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: A forty-eight-week, multicenter, randomized, double-blind, placebo-controlled study

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AEAnnelies E. van EdeTwitter (United States)RLRoland LaanRadboud University NijmegenMRM. J. RoodZiekenhuis Gelderse Vallei

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Ede et al. (2001) studied this question.

synapsesocial.com/papers/6a7007f92163a0a01bc43fcdhttps://doi.org/10.1002/1529-0131(200107)44:7<1515::aid-art273>3.0.co;2-7
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of Low-Dose Methotrexate in Rheumatoid Arthritis1985 · 882 citations
  2. 2Supplementation with Folic Acid during Methotrexate Therapy for Rheumatoid Arthritis: A Double-Blind, Placebo-Controlled Trial1994 · 361 citations
  3. 3Revised Criteria for the Classification of Rheumatoid Arthritis1990 · 7,736 citations
  4. 4EVALUATION OF THE DUTCH ARTHRITIS IMPACT MEASUREMENT SCALES (DUTCH-AIMS) IN PATIENTS WITH RHEUMATOID ARTHRITIS1989 · 37 citations
  5. 5CLINICAL STUDIES WITH AN ARTICULAR INDEX FOR THE ASSESSMENT OF JOINT TENDERNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS1968 · 1,351 citations