March 1, 1989Journal of NeuroscienceOpen Access

Open channel structure and ion binding sites of the nicotinic acetylcholine receptor channel

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Population

Clonal BC3H-1 muscle cells

Design

Preclinical

Authors

JDJA DaniBaylor College of Medicine

Discussion

Member takes

Implication

Refines nAChR pore model in animal systems; extends structural data but leaves open functional validation and clinical translation.

Structured PICO

Population

Clonal BC3H-1 muscle cells

Intervention

Patch-clamp techniques measuring permeability ratios and streaming potentials

Outcome

Structure and ion binding sites of the nicotinic ACh receptor channelsurrogate

The study provides structural insights into the nicotinic acetylcholine receptor channel, indicating a short narrow region with a single primary ion binding site.

Cite This Study

JA Dani (1989) studied this question.

synapsesocial.com/papers/6a700a98439bab0cabc2feae https://doi.org/10.1523/jneurosci.09-03-00884.1989

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Open channel structure and ion binding sites of the nicotinic acetylcholine receptor channel

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Open channel structure and ion binding sites of the nicotinic acetylcholine receptor channel

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider