What question did this study set out to answer?

This study aims to evaluate the discomfort and effectiveness of brachial artery flow-mediated dilation techniques using different cuff positions.

November 1, 1998Vascular MedicineOpen Access

Non-invasive assessment of brachial artery endothelial vasomotor function: the effect of cuff position on level of discomfort and vasomotor responses

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Why the study?

Does cuff position (above vs below the elbow) affect the level of discomfort and vasomotor responses during non-invasive assessment of brachial artery endothelial function?

Key Points

This study aims to evaluate the discomfort and effectiveness of brachial artery flow-mediated dilation techniques using different cuff positions.
54 subjects underwent flow-mediated dilation using cuff occlusion above and below the elbow.
Discomfort levels were measured using a visual analogue scale and compared to standard venipuncture.
27 subjects had cuff positions compared for their effect on flow responses and discomfort levels.
Cuff position above the elbow resulted in higher discomfort (1.9 cm) compared to venipuncture (1.0 cm, p=0.003).
Flow responses were significantly lower when the cuff was below the elbow (570% increase) compared to above (900%, p=0.005).
Discomfort at the below the elbow position was similar to venipuncture (1.6 cm vs. 1.0 cm, p=0.008).

Structured PICO

Does cuff position (above vs below the elbow) affect the level of discomfort and vasomotor responses during non-invasive assessment of brachial artery endothelial function?

Population

54 human subjects

Intervention

Cuff occlusion of the arm above the elbow for flow-mediated dilation assessment

Comparator

Standard venipuncture (for discomfort comparison) and cuff occlusion below the elbow (for vasomotor response and discomfort comparison in a subset of 27 subjects)

Outcome

Level of discomfort assessed using a visual analogue scale, percentage increase in flow, and flow-mediated dilationsurrogate

Non-invasive assessment of flow-mediated brachial artery dilation is well tolerated, though cuff position significantly affects both the magnitude of the vasomotor response and patient discomfort.

Discussion

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Implication

Cuff position influences FMD responses and tolerability; leaves open optimal placement pending prospective validation.

Cite This Study

Mannion et al. (1998) studied this question.

synapsesocial.com/papers/6a700ccbfe4101aa97dffd5f https://doi.org/10.1177/1358836x9800300401

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Bookmark

Non-invasive assessment of brachial artery endothelial vasomotor function: the effect of cuff position on level of discomfort and vasomotor responses

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Non-invasive assessment of brachial artery endothelial vasomotor function: the effect of cuff position on level of discomfort and vasomotor responses

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

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