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May 1, 1980Journal of Biological ChemistryOpen Access

3-Carbanionic substrate analogues bind very tightly to fumarase and aspartase.

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DPDavid PorterAuckland City HospitalHBHarold J. BrightUniversity of the Sciences

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Porter et al. (1980) studied this question.

synapsesocial.com/papers/6a700d5ee5469ee92be0d417https://doi.org/10.1016/s0021-9258(19)85564-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Studies of the Enzyme Fumarase. V.1 Calculation of Minimum and Maximum Values of Constants for the General Fumarase Mechanism21957 · 19 citations
  2. 2The Mechanism of the β-Methylaspartase Reaction1964 · 38 citations
  3. 3Direct Evidence for Carbanions and Covalent N5-Flavin-Carbanion Adducts as Catalytic Intermediates in the Oxidation of Nitroethane by d-Amino Acid Oxidase1973 · 151 citations
  4. 4Rigorous least squares adjustment: Application to some non-linear equations, I1965 · 295 citations
  5. 5A Correlation of Reaction Rates1955 · 3,584 citations