Action of Cortisone on Tissue Reactions of Inflammation and Repair with Special Reference to the Eye

IT has already been shown in the two previous articles in this issue of the Journal that the clinical effects of cortisone and ACTH have excited much interest and a very extensive literature; the reports dealing with their effects upon the fundamental reactions of inflammation and repair, however, are as yet relatively few in number and there is still considerable disagreement over some of the more important problems. This is unfortunate and to some extent illogical, but it is only to be expected that agents which can exert an effect so dramatic upon many ocular diseases should be exploited clinically to the fullest possible extent at the earliest moment, even although the theoretical foundation for their action remains obscure.