What question did this study set out to answer?

To evaluate the relationships among muscle strength, cross-sectional area, and lung disease severity in COPD patients.

Peripheral Muscle Weakness in Patients with Chronic Obstructive Pulmonary Disease

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Evaluates muscle strength and atrophy in patients with COPD, highlighting significance for exercise capacity.

To evaluate the relationships among muscle strength, cross-sectional area, and lung disease severity in COPD patients.
Measured muscle strength and cross-sectional area in 34 COPD patients and 16 age-matched controls.
Used computed tomography to assess thigh muscle area.
Analyzed correlations between muscle strength, muscle atrophy, and FEV1 values.
Strength of three muscle groups reduced in COPD compared to controls (p < 0.05).
Right thigh muscle CSA was smaller in COPD (83.4 +/- 16.4 cm2 vs. 109.6 +/- 15.6 cm2, p < 0.0001).
Quadriceps strength correlated positively with FEV1 (r = 0.55, p < 0.0005), indicating stronger muscle links to airflow obstruction.

Bernard et al. (1998) studied this question.

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