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May 17, 2002Biochemistry

Interactions of Amyloid β-Protein with Various Gangliosides in Raft-Like Membranes:  Importance of GM1 Ganglioside-Bound Form as an Endogenous Seed for Alzheimer Amyloid

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Authors

AKAtsuko KakioKyoto UniversitySNSei‐ichi NishimotoUniversity of FukuiKYKatsuhiko YanagisawaUniversity of Tsukuba

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Kakio et al. (2002) studied this question.

synapsesocial.com/papers/6a701070ac440176ef28b5bbhttps://doi.org/10.1021/bi0255874
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Glycosphingolipids Are Not Essential for Formation of Detergent-resistant Membrane Rafts in Melanoma Cells1999 · 159 citations
  2. 2Membrane Disruption by Alzheimer β-Amyloid Peptides Mediated through Specific Binding to Either Phospholipids or Gangliosides1996 · 333 citations
  3. 3Amyloid β‐protein (Aβ) associated with lipid molecules: immunoreactivity distinct from that of soluble Aβ1997 · 43 citations
  4. 4Topographical Atlas of the Gangliosides of the Adult Human Brain1984 · 92 citations
  5. 5Cholesterol-dependent Formation of GM1 Ganglioside-bound Amyloid β-Protein, an Endogenous Seed for Alzheimer Amyloid2001 · 410 citations