Key result
Gray matter-rich neocortical areas had a four- to fivefold higher ganglioside content than white matter-rich regions, with distinct regional preferences for a- and b-pathway gangliosides.
Population
40 different brain samples from adult human brain, including neocortical, archicortical, paleocortical…
Design
Other
Authors
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No immediate clinical implications; leaves open functional correlations with regional brain systems.
Observational (n=40)
This study maps the regional distribution of gangliosides in the adult human brain, revealing distinct biochemical patterns that may correlate with specific functional systems such as glutaminergic synaptic transmission.
Kraĉun et al. (1984) reported an observational. Brain region was evaluated on Total content of ganglioside-sialic acid and the ganglioside pattern. Gray matter-rich neocortical areas had a four- to fivefold higher ganglioside content than white matter-rich regions, with distinct regional preferences for a- and b-pathway gangliosides.