Rapid intersite transfer of acetyl groups and movement of pyruvate dehydrogenase component in the kidney pyruvate dehydrogenase complex.

The resolved pyruvate dehydrogenase component is a tetramer containing two (Y subunits and two p subunits.It is assumed that in an a& tetramer, there are two catalytical units, i.e. one per a@ unit.This is consistent with previous studies (9) indicating one T P P or one TTPP binding site per ap unit.