June 30, 2012Seminars in Thrombosis and HemostasisOpen Access

External Quality Assurance for Heparin Monitoring

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Population

Heparin-containing plasma samples with concentrations ranging from 0 to 1.4 U/mL evaluated in the Royal…

Follow-up

8-year period

Authors

RBRoslyn BonarRoyal College of Pathologists of Australasia EFEmmanuel J. FavaloroVascular Medicine KMKatherine MarsdenForeign and Commonwealth Office

Discussion

Member takes

Implication

Anti-Xa assay variability may affect heparin monitoring reliability; supports broader external quality assurance programs.

Structured PICO

Population

Heparin-containing plasma samples with concentrations ranging from 0 to 1.4 U/mL evaluated in the Royal College of Pathologists of Australasia Haematology Quality Assurance Program.

Intervention

Laboratory evaluation of activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen, and anti-Xa assays.

Outcome

Interlaboratory variation (coefficient of variation, CV) and test performance.surrogate

There is substantial interlaboratory variation in anti-Xa assays for heparin monitoring, underscoring the importance of external quality assurance programs.

Cite This Study

Bonar et al. (2012) studied this question.

synapsesocial.com/papers/6a7013fbac440176ef28b9b2 https://doi.org/10.1055/s-0032-1321954

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External Quality Assurance for Heparin Monitoring

Discussion

Member takes

Implication

Structured PICO

Cite This Study

External Quality Assurance for Heparin Monitoring

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider