Why the study?
Antiplatelet therapy has demonstrated potential benefits across various cardiovascular conditions, but its role in sepsis remains less clear.
Does antiplatelet therapy reduce mortality in patients with sepsis?
Comparison
Antiplatelet therapy vs no antiplatelet therapy
Design
Systematic review and meta-analysis
Authors
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Antiplatelet therapy was associated with lower short-term sepsis mortality; supports RCTs before practice change.
Does antiplatelet therapy reduce mortality in patients with sepsis?
Antiplatelet therapy appears to safely lower the risk of short-term mortality in patients with sepsis, though the certainty of evidence is low.
Wang et al. (2025) studied this question.
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