Why the study?
How does the use of hormonal contraceptives and HRT affect the risk of venous thromboembolism and peri-operative management in women undergoing surgery?
How does the use of hormonal contraceptives and HRT affect the risk of venous thromboembolism and peri-operative management in women undergoing surgery?
This review highlights the need to consider the increased risk of venous thromboembolism associated with hormonal contraceptives and HRT when managing women in the peri-operative period.
May warrant individualized peri-operative VTE risk assessment in hormonal therapy users; leaves open optimal management strategies pending prospective data.
Women taking combined hormonal contraceptives or hormone replacement therapy (HRT) have an increased risk of developing venous thromboembolism, compared to non-users. Surgery itself carries a risk of thromboembolism, the incidence of which varies with the nature of the procedure. In this article, the third in our series on drug therapy in the peri-operative period, we review the thromboembolic effects of oral contraceptives and HRT and consider how these affect management around the time of surgery.
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A 1999 study studied this question.
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