Cognitive Functioning and Health-Related Quality of Life 1 Year After Aneurysmal Subarachnoid Hemorrhage in Preoperative Comatose Patients (Hunt and Hess Grade V Patients)

In Brief OBJECTIVE The objective of this study was to determine cognitive functioning and health-related quality of life 1 year after aneurysmal subarachnoid hemorrhage in preoperative comatose patients (Hunt and Hess Grade V patients). METHODS Patients who were comatose at hospital arrival and thereafter were investigated for 1 year using a comprehensive neuropsychological test battery and 2 HRQOL questionnaires. RESULTS Thirty-five of 70 patients survived the bleed, and 26 underwent neuropsychological testing. Two distinct patient groups emerged, one (n = 14) with good cognitive function, having mild deficits only, and the other (n = 12) with poor cognitive and poor motor function. Patients performing poorly were older (P = .04), had fewer years of education (P = .005) and larger preoperative ventricular scores, and were more often shunted (P = .02). There were also differences between the 2 groups in the Glasgow Outcome Scale (P = .001), the modified Rankin Scale (P = .001), and employment status. HRQOL was more reduced in patients with poor cognitive function. CONCLUSION A high fraction of survivors among preoperative comatose aneurysmal SAH patients (Hunt and Hess grade V) recover to good physical and cognitive function, enabling them to live a normal life. OBJECTIVE: The objective of this study was to determine cognitive functioning and health related quality of life one year after aneurysmal subarachnoid hemorrhage in preoperative comatose patients. METHODS: Patients were investigated for one year using a comprehensive neuropsychological test battery and two HRQOL questionnaires. RESULTS: Thirty-five of 70 patients survived the bleed, and 26 underwent neuropsychological testing. Two distinct patient groups emerged; one (n = 14) with good cognitive function, and the other (n = 12) with poor cognitive and motor function. Patients performing poorly were older (p = 0.04), had fewer years of education, (p = 0.005) larger preoperative ventricular scores, and were more often shunted (p = 0.02). There were also differences between the two groups in the Glasgow Outcome Scale (p = 0.001), modified Rankin Scale (p = 0.001), and employment status. HRQOL was more reduced in patients with poor cognitive function. CONCLUSION: A high fraction of survivors among preoperative comatose aneurysmal SAH patients (Hunt and Hess grade V patients) recover to a good physical and cognitive function.