Chronic obstructive pulmonary disease (COPD) is increasinglyrecognized as a major health care problem and the numberof publications in the scientific literature is a reflection of thisincreased awareness. This update cannot do justice to allnewly available information, but it does represent a selection ofarticles that were considered to be of sufficient general interestto warrant further discussion.
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Rabe et al. (2007) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: