Why the study?
Does laser thrombolysis improve myocardial perfusion in a patient with a large thrombus in the right coronary artery refractory to tirofiban?
Does laser thrombolysis improve myocardial perfusion in a patient with a large thrombus in the right coronary artery refractory to tirofiban?
Laser thrombolysis may be a viable alternative for treating large, refractory thrombus-containing lesions in acute coronary syndromes.
May support laser thrombolysis in refractory coronary thrombus; hypothesis-generating and should not change practice without further evidence.
The presence of thrombus in the lesion before balloon angioplasty increases the complications arising from mechanical intervention. It is known that the use of Gp llb/llla receptor blockers before the intervention enhances the reliability of the procedure. Laser thrombolysis was applied to a patient who underwent coronary angiography due to recurrent chest pain after thirty six hour administration of tirofiban and who was found to have a thrombus so large as to block the distal vessel bed of the right coronary artery. Following the procedure, the entire thrombus was broken down and Grade III distal myocardial perfusion was achieved. This case is important in demonstrating that laser application is a viable alternative in such instances, especially considering that intervention in acute coronary syndromes is on the increase and cardiologists will frequently encounter such cases.
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İlkay et al. (2003) studied this question.
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