Why the study?
Female patients undergoing abdominal aortic aneurysm repair have worse outcomes than men, prompting investigation into sex differences in achieving textbook outcomes after open and endovascular repair.
Does female sex reduce the likelihood of achieving a textbook outcome in adults undergoing elective abdominal aortic aneurysm repair compared to male sex?
Does female sex reduce the likelihood of achieving a textbook outcome in adults undergoing elective abdominal aortic aneurysm repair compared to male sex?
Women undergoing elective AAA repair are significantly less likely to achieve a textbook outcome than men, but achieving this outcome eliminates sex differences in 1-year survival.
Answers are grounded in this paper and cite their sources.
Women less likely to achieve textbook outcome after AAA repair; leaves open whether sex-specific strategies improve TO rates.
BACKGROUND: Female patients with abdominal aortic aneurysms (AAAs) undergoing repair have worse outcomes than men. Textbook outcomes (TOs) have been described as a metric to direct quality improvement efforts and assess institutional performance. We investigated sex differences among patients achieving a TO after open (OAR) and endovascular aortic aneurysm repair (EVAR). STUDY DESIGN: Vascular Quality Initiative registry data from 80,948 patients undergoing elective AAA repair were reviewed. TO was defined as the absence of major medical or surgical complication, prolonged postoperative length of stay (based on the 75th percentile of the cohort), reintervention, or mortality and nonhome discharge. EVAR and OAR cohorts were analyzed separately, stratified by TO and sex, and compared based on patient demographics, outcomes, and 1-year survival. RESULTS: More men had a TO compared with women (EVAR 80% vs 67%; OAR 54% vs 47%, p < 0.001, respectively). Obstacles for achieving TO for women were prolonged postoperative length of stay, surgical complications, and nonhome discharge. TO was associated with improved 1-year survival in EVAR and OAR. High-volume center status (based on case volume quartiles) was not associated with TO for EVAR but was associated with TO for men undergoing OAR. CONCLUSIONS: Women are less likely to achieve a TO regardless of surgical approach, and they have a lower 1-year survival than men when they do not. Importantly, when women do achieve a TO, there are no sex differences in 1-year survival. TO is as a patient-centered quality standard and provides objective support for patient-provider decision-making and expectations and may serve as a quality metric that should be implemented to mitigate sex disparities. Further investigation using multilevel modeling to examine patient, provider, and facility variables that impact TO is warranted.
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Filiberto et al. (2025) studied this question.
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