Why the study?
Does higher trans fat intake increase the risk of incident ischemic stroke in generally healthy postmenopausal women?
Population
87,025 generally healthy postmenopausal women enrolled in the Women's Health Initiative Observational Study
Comparison
Highest quintile of trans fat intake vs Lowest quintile of trans fat intake
Design
Cohort
Follow-up
663,041 person-years
Authors
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May support trans fat reduction counseling in postmenopausal women; extends observational data but leaves causality and aspirin interaction open.
Does higher trans fat intake increase the risk of incident ischemic stroke in generally healthy postmenopausal women?
Higher trans fat intake is associated with an increased risk of ischemic stroke in postmenopausal women, an effect that may be attenuated by aspirin use.
Yaemsiri et al. (2012) studied this question.
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