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January 1, 1994AJP Cell Physiology

Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis

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Authors

HHHameda B. HussainWashington University in St. LouisLSLaurie P. ShornickSaint Louis UniversityVSVickie R. ShannonThe University of Texas MD Anderson Cancer Center

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Cite This Study

Hussain et al. (1994) studied this question.

synapsesocial.com/papers/6a701dd1439bab0cabc30544https://doi.org/10.1152/ajpcell.1994.266.1.c243
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Arachidonic acid metabolism in guinea pig Langerhans cells: studies on cyclooxygenase and lipoxygenase pathways.1987 · 61 citations
  2. 2Overexpression of Transforming Growth Factor α in Psoriatic Epidermis1989 · 534 citations
  3. 3Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.1975 · 588 citations
  4. 4A regiospecific monooxygenase with novel stereopreference is the major pathway for arachidonic acid oxygenation in isolated epidermal cells.1989 · 70 citations
  5. 5An enzymatic method for distinguishing the stereoisomers of 12-hydroxyeicosatetraenoic acid in human epidermis and psoriatic scale1989 · 13 citations