Why the study?
Does primary percutaneous coronary intervention reduce the 6-month composite incidence of death, recurrent MI, and stroke compared to thrombolytic therapy in patients with acute STEMI presenting to hospitals without on-site cardiac surgery?
Population
451 thrombolytic-eligible patients with acute myocardial infarction of less than 12 hours' duration…
Comparison
Primary percutaneous coronary intervention (PCI) vs Accelerated tissue plasminogen activator
Design
RCT, randomly assigned
Follow-up
6 months
Authors
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Primary PCI reduces 6-month events versus thrombolysis in STEMI without on-site surgery; extends RCT evidence to community hospitals.
Does primary percutaneous coronary intervention reduce the 6-month composite incidence of death, recurrent MI, and stroke compared to thrombolytic therapy in patients with acute STEMI presenting to hospitals without on-site cardiac surgery?
Primary PCI performed at community hospitals without on-site cardiac surgery yields superior clinical outcomes at 6 months compared to thrombolytic therapy for patients with acute STEMI.
Thomas Aversano (2002) studied this question.
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