September 8, 2010Journal of Cardiothoracic SurgeryOpen Access

Difference between pre-operative and cardiopulmonary bypass mean arterial pressure is independently associated with early cardiac surgery-associated acute kidney injury

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Why the study?

Does a large delta MAP during cardiopulmonary bypass increase the risk of early acute kidney injury in high-risk patients undergoing cardiac surgery?

Population

157 consecutive high-risk patients undergoing cardiac surgery with cardiopulmonary bypass, mean age 65.9 ±…

Design

Cohort

Follow-up

24 hours

Authors

HKHussein D. KanjiUniversity of British Columbia CSCostas SchulzeKelowna General Hospital MHMarilou Hervas‐MaloUniversity of Alberta

Discussion

Member takes

Implication

Supports MAP monitoring during CPB; leaves open whether minimizing delta MAP prevents CSA-AKI.

Structured PICO

Does a large delta MAP during cardiopulmonary bypass increase the risk of early acute kidney injury in high-risk patients undergoing cardiac surgery?

Population

157 consecutive high-risk patients undergoing cardiac surgery with cardiopulmonary bypass (CPB), mean age 65.9 ± 14.7 years, 70.1% male.

Intervention

Delta MAP (pre-operative MAP minus average MAP during CPB) and CPB flow rate

Outcome

Early cardiac surgery-associated acute kidney injury (CSA-AKI), defined by a minimum RIFLE class - RISK within the first 24 hours post surgery

A large difference between pre-operative and intra-operative mean arterial pressure (delta MAP ≥26 mmHg) is independently associated with early acute kidney injury after cardiac surgery.

Cite This Study

Kanji et al. (2010) studied this question.

synapsesocial.com/papers/6a701ed2fe4101aa97e00559 https://doi.org/10.1186/1749-8090-5-71

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Difference between pre-operative and cardiopulmonary bypass mean arterial pressure is independently associated with early cardiac surgery-associated acute kidney injury

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Difference between pre-operative and cardiopulmonary bypass mean arterial pressure is independently associated with early cardiac surgery-associated acute kidney injury

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider