Why the study?
Congenital heart defects are common and carry high morbidity, and early detection remains challenging since some defects are undetectable on conventional four-chamber views.
Does measurement of fetal cardiac axis improve detection of congenital heart defects in fetuses during early gestation?
Does measurement of fetal cardiac axis improve detection of congenital heart defects in fetuses during early gestation?
Measurement of the fetal cardiac axis in the first trimester may serve as a reliable marker for early detection of congenital heart defects, improving upon the conventional four-chamber view.
May aid early CHD detection via first-trimester axis measurement; leaves open validation before clinical adoption.
Congenital heart defects represent the most common structural anomalies observed in the fetal population, and they are often associated with significant morbidity and mortality. The fetal cardiac axis, which indicates the orientation of the heart in relation to the chest wall, is formed by the angle between the anteroposterior axis of the chest and the interventricular septum of the heart. Studies conducted during the first trimester have demonstrated promising outcomes with respect to the applicability of cardiac axis measurement in fetuses with congenital heart defects as well as fetuses with extracardiac and chromosomal anomalies, which may result in improved health outcomes and reduced healthcare costs. The main aim of this review article was to highlight the cardiac axis as a reliable and powerful marker for the detection of congenital heart defects during early gestation, including defects that would otherwise remain undetectable through the conventional four-chamber view.
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Carrasco et al. (2024) studied this question.
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