Report of a patient co-infected with HTLV-I and HIV presenting with polymyositis.
Alerts clinicians to HTLV-I/HIV co-infection in polymyositis; hypothesis-generating and should not yet change practice.
EPIDEMIOLOGIC studies of the seroprevalence of antibodies to human T-cell leukemia virus Type I (HTLV-I) have associated this viral infection with leukemia, a chronic myelopathy,1 2 3 4 5 and polymyositis.2 In Jamaica, where the seroprevalence of HTLV-I is high (ranging from 7 to 18 percent among persons 30 to 69 years old6), all seven patients with polymyositis were seropositive for HTLV-I. In the United States, where the prevalence of HTLV-I infection is less than 0.1 percent,7 1 of 49 patients with polymyositis was HTLV-I seropositive. Recently, another retrovirus, the human immunodeficiency virus (HIV), has also been associated with a progressive myopathy.8 9 10 11 12 13 All . . .
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Wiley et al. (1989) studied this question.
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