Why the study?
Does right ventricular myocardial involvement increase the risk of long-term cardiac death in patients who survived to discharge after acute inferior STEMI?
Does right ventricular myocardial involvement increase the risk of long-term cardiac death in patients who survived to discharge after acute inferior STEMI?
Right ventricular myocardial involvement does not increase the risk of long-term mortality in patients surviving to discharge after acute inferior STEMI.
No increased 3-year mortality with RVI after inferior STEMI discharge; leaves open whether acute-phase observations warrant prospective long-term validation.
OBJECTIVES: To investigate the long-term impact of right ventricular myocardial involvement (RVI) after acute inferior ST-segment elevation myocardial infarction (STEMI). METHODS: A total of 1208 consecutive patients, who survived to discharge after hospitalization for acute inferior STEMI, were studied. Patients were divided into those with (n = 459) or without (n = 749) of RVI involvement, defined as ST-segment elevation > or =1 mm in V4R. Cardiac death by 3 years was the primary study end point. RESULTS: By the end of follow-up, 207 (17.1%) patients had died. Patients with RVI were at similar risk for death at 3 years than those without (17.6% vs 16.8%, hazard ratio 1.1, 95% confidence interval 0.8-1.4, P = .79). By multivariate Cox analysis, several variables, but not RVI, were associated with the incidence of 3 years cardiac death. CONCLUSIONS: Right ventricular myocardial involvement does not portend any increased risk for long-term mortality, in patients who survived to discharge after hospitalization for acute inferior STEMI.
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Foussas et al. (2009) studied this question.
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