Combined Effect of Age and Right Ventricular Involvement on Acute Inferior Myocardial Infarction Prognosis
Key result
Right ventricular involvement in acute inferior myocardial infarction was associated with higher in-hospital mortality (22% vs 6%, P<0.0001), an effect that was significant only in older patients.
Why the study?
Does right ventricular involvement increase in-hospital mortality in patients with acute inferior myocardial infarction, and does this effect depend on age?
Population
798 consecutive patients admitted to the coronary care unit within 48 hours of symptom onset with acute…
Comparison
Presence of right ventricular involvement… vs Absence of right ventricular involvement
Design
Cohort
Follow-up
In-hospital
Authors
Discussion
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Member takes
Implication
RV involvement may flag higher-risk older inferior MI patients; extends prognostic data but leaves targeted interventions open.
Study Design
Type
Cohort (n=798)
Structured PICO
Does right ventricular involvement increase in-hospital mortality in patients with acute inferior myocardial infarction, and does this effect depend on age?
P
Population
798 consecutive patients admitted to the coronary care unit within 48 hours of symptom onset with acute inferior myocardial infarction, evaluated for in-hospital clinical outcomes.
E
Exposure
Presence of right ventricular involvement (RVI) diagnosed by ECG and/or echocardiographic criteria
C
Comparator
Absence of right ventricular involvement
O
Outcome
In-hospital mortalityhard clinical
Main Result
Absolute Event Rate: 22% vs 6%
p-value: p=<0.0001
Right ventricular involvement in acute inferior myocardial infarction significantly increases in-hospital mortality primarily in elderly patients, while having a non-significant effect in younger subjects.
Cite This Study
Bueno et al. (1998) conducted a cohort in Acute inferior myocardial infarction (AIMI) (n=798). Right ventricular involvement (RVI) vs. No right ventricular involvement was evaluated on In-hospital mortality (p=<0.0001). Right ventricular involvement in acute inferior myocardial infarction was associated with higher in-hospital mortality (22% vs 6%, P<0.0001), an effect that was significant only in older patients.