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Sympathetic denervation increases myocardial fat and carbohydrate accumulation in canine hearts, providing evidence for autonomic regulation of cardiac metabolism.
Sympathetic denervation of the canine heart, which is extensive enough to insure depletion of myocardial catecholamines, results in an increased accumulation of myocardial fat and carbohydrate substances. Myocardial histamine, ubiquinone and nitrogen contents are unaffected. These observations provide additional evidence for the participation of the autonomic nervous system in the regulation of cardiac metabolism.
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Jellinek et al. (1964) studied this question.
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