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Improved solutions of the diffusion equation for time-resolved and steady-state spatially resolved reflectance are investigated for the determination of the optical coefficients of semi-infinite turbid media such as tissue. These solutions are derived for different boundary conditions at the turbid-medium-air interface and are compared with Monte Carlo simulations. Relative reflectance data are fitted in the time domain, whereas relative and absolute reflectance are investigated in the steady-state domain. It is shown that the error in deriving the optical coefficients is, especially for steady-state spatially resolved reflectance, considerably smaller for the solutions under study than for the commonly used solutions. Analysis of experimental measurements of absolute steady-state spatially resolved reflectance confirms these results.
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Kienle et al. (1997) studied this question.
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