Why the study?
Is there a higher prevalence of sleep-disordered breathing in patients with Marfan's syndrome compared to matched controls?
Population
25 patients who fulfilled the diagnostic criteria for Marfan's syndrome.
Design
Case-control
Authors
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Marfan syndrome was associated with higher OSA prevalence; hypothesis-generating and should not yet change practice.
Is there a higher prevalence of sleep-disordered breathing in patients with Marfan's syndrome compared to matched controls?
Patients with Marfan's syndrome have a significantly higher prevalence of obstructive sleep apnea compared to matched controls, suggesting that symptoms of OSA should be routinely sought in this population.
Cistulli et al. (1993) studied this question.
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