Background Review Paper on Total Fat, Fatty Acid Intake and Cancers

This report has benefited from these advances, and aims to present new evidence with a potential impact upon dietary recommendations.In this background review paper, colorectal, prostate, breast, endometrial and ovary cancers will be covered successively, and the effect of total fat will be evaluated for each.The effect of specific FA (saturated, monounsaturated, n-6 and n-3 polyunsaturated, trans FA) will be evaluated on colorectal, prostate and breast cancer.In the latter, the effects of combined inadequate intakes of n-6 and n-3 polyunsaturated FA and of polyunsaturated FA and antioxidants have been shown in some studies, and will also be discussed. MethodThe WCRF/AICR database was updated with studies published after 2006, although some older studies were later included.