Why the study?
Do oral macrolide antibiotics increase the risk of ventricular arrhythmia in older adults compared to nonmacrolide antibiotics?
Do oral macrolide antibiotics increase the risk of ventricular arrhythmia in older adults compared to nonmacrolide antibiotics?
In older adults, macrolide antibiotics do not increase the 30-day risk of ventricular arrhythmia compared to nonmacrolide antibiotics, suggesting that current FDA warnings may be overstated.
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No elevated arrhythmia risk with macrolides in older adults; leaves open whether regulatory warnings warrant revision pending RCTs.
Trac et al. (2016) studied this question.
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